Feasibility of a positive psychology intervention (PATH) in allogeneic hematopoietic stem cell transplantation survivors: Randomized pilot trial design and methods
Authors: "[\"Hermioni L Amonoo\",\"Elizabeth F Collins\",\"Lauren E Harnedy\",\"Stephanie J Lee\",\"Areej El-Jawahri\"]"
Journal: Contemporary Clinical Trials
"[\"hematologic malignancies\",\"hematopoietic stem cell transplantation\",\"positive psychology\",\"psycho-oncology\",\"randomized controlled trial\"]"
Abstract
Background: Although patients undergoing allogeneic hematopoietic stem cell transplantation experience low levels of positive psychological well-being, interventions that specifically boost PPWB in this population are lacking. We will conduct a single-institution RCT of a novel nine-week phone-delivered manualized positive psychology intervention compared to usual transplant care in 70 HSCT survivors. The PATH intervention, tailored to the needs of HSCT survivors in the acute recovery phase, focuses on gratitude, strengths, and meaning. Our primary aims are to determine feasibility and acceptability. Our secondary aim is to test the preliminary efficacy of the intervention on patient-reported outcomes such as anxiety symptoms and quality of life.