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Oral S-ketamine effective after deep brain stimulation in severe treatment-resistant depression and extensive comorbidities.

Authors: Veraart JKE, Kamphuis J, Schlegel M, Schoevers RA
Journal: BMJ case reports
depressive disorder therapeutic indications Administration, Oral Anti-Anxiety Agents Antidepressive Agents Antipsychotic Agents Clozapine Deep Brain Stimulation Depressive Disorder, Treatment-Resistant Electroconvulsive Therapy Female Glycopyrrolate Hallucinations Humans Ketamine

Abstract

This case report describes successful maintenance treatment with oral S-ketamine in a patient with severe depression, who previously was resistant to electroconvulsive therapy and deep brain stimulation, and who also had comorbid psychotic and obsessive compulsive symptoms.